This can help improve the symptoms of low testosterone, like low libido and lack of energy. With TRT, you take a manufactured form of testosterone to regulate your levels. Topical androgens like testosterone have been used and studied in the treatment of cellulite in women. Testosterone, as esters such as testosterone undecanoate or testosterone buciclate, has been studied and promoted as a male contraceptive analogous to estrogen-based contraceptives in women. A similar 2012 review also found increased exercise capacity and reasoned the benefits generlizable to women. Prescription anabolic steroids work in different ways to treat conditions. This is considered an off-label, or non-FDA-approved, use of the medication. They’re manufactured drugs that closely resemble cortisol, a hormone that your adrenal glands produce naturally. General steroids, called corticosteroids, are medications that reduce inflammation and the activity of your immune system. Approximately 3 to 4 million people in the United States use anabolic steroids for nonmedical purposes. Some athletes, bodybuilders and others misuse these drugs in an attempt to enhance performance and/or improve their physical appearance. There are multiple forms of topical testosterone available. Store topical testosterone in a safe place to protect it from theft. Keep topical testosterone out of the reach of children. Do not share topical testosterone with other people, even if they have the same condition as you. Testosterone is under development in a low-dose intranasal formulation for the treatment of anorgasmia in women. Otherwise considered an adverse effect of testosterone, reduced spermatogenesis can be further suppressed with the addition of a progestin such as norethisterone enanthate or levonorgestrel butanoate, improving the contraceptive effect. Testosterone replacement can significantly improve exercise capacity, muscle strength and reduce QT intervals in men with chronic heart failure (CHF).